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Guido Wassink Selected Research

gardiquimod

1/2020TLR7 agonist modulation of postasphyxial neurophysiological and cardiovascular adaptations in preterm fetal sheep.
1/2019Protective effects of delayed intraventricular TLR7 agonist administration on cerebral white and gray matter following asphyxia in the preterm fetal sheep.

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Guido Wassink Research Topics

Disease

14Hypothermia
06/2022 - 01/2015
13Ischemia
06/2022 - 03/2006
13Asphyxia (Suffocation)
01/2021 - 02/2003
11Hypoxia (Hypoxemia)
01/2021 - 03/2006
10Brain Injuries (Brain Injury)
01/2021 - 02/2003
9Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain)
06/2022 - 01/2015
8Inflammation (Inflammations)
06/2022 - 11/2013
6Brain Ischemia (Cerebral Ischemia)
06/2022 - 12/2015
5Brain Diseases (Brain Disorder)
01/2022 - 01/2017
5Gliosis
03/2020 - 11/2013
5Hypotension (Low Blood Pressure)
03/2020 - 06/2014
4Infections
10/2020 - 11/2013
3Premature Birth (Birth, Premature)
03/2020 - 04/2017
2Chorioamnionitis
10/2020 - 01/2018
2Seizures (Absence Seizure)
09/2020 - 01/2018
1Demyelinating Diseases (Demyelinating Disease)
01/2021
1Sepsis (Septicemia)
10/2020
1Tachycardia (Tachyarrhythmias)
03/2020
1Neuroinflammatory Diseases
03/2020
1Fever (Fevers)
01/2019
1Obesity
01/2018
1Pre-Eclampsia (Preeclampsia)
01/2018
1Premature Obstetric Labor (Premature Labor)
01/2018
1Eclampsia
03/2016
1Brain Edema (Cerebral Edema)
01/2012
1Alzheimer Disease (Alzheimer's Disease)
11/2007
1Paralysis (Palsy)
07/2007
1Edema (Dropsy)
04/2007
1Hypertension (High Blood Pressure)
10/2005

Drug/Important Bio-Agent (IBA)

19salicylhydroxamic acid (SHAM)IBA
06/2022 - 03/2006
5ErythropoietinFDA Link
01/2021 - 03/2017
4Myelin Basic ProteinIBA
01/2021 - 01/2016
4LipopolysaccharidesIBA
11/2020 - 08/2014
3Anticonvulsants (Antiepileptic Drugs)IBA
01/2018 - 04/2015
2ConnexinsIBA
09/2020 - 12/2015
2Peptides (Polypeptides)IBA
09/2020 - 12/2015
2gardiquimodIBA
01/2020 - 01/2019
2Caspase 3 (Caspase-3)IBA
01/2020 - 01/2019
2CytokinesIBA
01/2019 - 08/2014
2GlucocorticoidsIBA
12/2018 - 11/2013
2MagnesiumIBA
12/2018 - 03/2016
2Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric
01/2018 - 04/2017
2Electron Transport Complex IV (Cytochrome c Oxidase)IBA
01/2012 - 04/2007
2Dizocilpine Maleate (Dizocilpine)IBA
03/2006 - 03/2006
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
03/2006 - 03/2006
1LipidsIBA
06/2022
1gamma-Aminobutyric Acid (GABA)IBA
09/2020
1Connexin 43 (Connexin43)IBA
09/2020
1Etanercept (Enbrel)FDA Link
03/2020
1InterleukinsIBA
03/2020
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2020
1Interleukin-6 (Interleukin 6)IBA
03/2020
1Interleukin-10 (Interleukin 10)IBA
03/2020
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
03/2020
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2020
1Glial Fibrillary Acidic ProteinIBA
01/2019
1GlycogenIBA
12/2018
1Pharmaceutical PreparationsIBA
01/2018
1Adrenergic Agents (Adrenergic Drugs)IBA
11/2016
1Cholinergic Agents (Cholinergics)IBA
11/2016
1Nuclear Proteins (Protein, Nuclear)IBA
01/2016
1HMGB1 Protein (HMG1)IBA
01/2016
1Analgesics (Analgesic Drugs)IBA
04/2015
1Hypnotics and Sedatives (Sedatives)IBA
04/2015
1NitritesIBA
12/2014
1Nitric Oxide Synthase (NO Synthase)IBA
12/2014
1Hemoglobins (Hemoglobin)IBA
01/2012
1CholesterolIBA
11/2007
1N-Methylaspartate (NMDA)IBA
03/2006
1Glutamate Receptors (Glutamate Receptor)IBA
03/2006
1AcidsIBA
10/2005
1Proteins (Proteins, Gene)FDA Link
02/2003
1Nerve Growth Factor (NGF)IBA
02/2003
1Nerve Growth Factors (Neurotrophins)IBA
02/2003
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
02/2003
1Brain-Derived Neurotrophic Factor (BDNF)IBA
02/2003

Therapy/Procedure

18Induced Hypothermia
06/2022 - 12/2014
7Therapeutics
01/2021 - 11/2013
6Rewarming
06/2022 - 01/2015
4Intraventricular Infusions
09/2020 - 12/2015
3Intravenous Infusions
01/2021 - 03/2017
1Immunomodulation
06/2022
1Artificial Respiration (Mechanical Ventilation)
10/2020
1Aftercare (After-Treatment)
10/2019
1Sympathectomy (Sympathectomies)
06/2014
1Anesthesia
07/2007